IE 8 Beta 2 is out, and with it comes a host of new issues for web developers.
The KB Article "Some Web sites may not be displayed correctly or work correctly in Windows Internet Explorer 8 Beta 2" as it's title suggests, offers some guidance on how to deal with these issues from a developer perspective.
As I understand it, IE 8 by default runs in "Standards Mode" which will cause a fair amount of disruption for users when they surf to a page with a lot of IE 7 and previous, code.
The article listed above shows a bunch of work around methods, some dealing with changing IE 8's default handling of web sites, others that are applied at the web site itself.
Well worth a read for both users and developers.
IE 8 Beta 2 is available here: http://www.microsoft.com/windows/internet-explorer/beta/